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MEDICAL PROBLEMS: BRIEF
REVIEWS—ACUTE RENAL FAILURE
Michael J Katz
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Acute renal failure (ARF) is a sudden and significant decrease in the kidneys’ filtration capabilities, and within hours or days, the levels of creatinine and other waste products build up in the systemic circulation. ARF occurs in approximately 5% of all patients admitted to hospitals. It often results from accidents, such as severe burns and trauma, that cause large losses in body fluid. A number of drugs can cause ARF. Hospital procedures can also cause ARF, and ARF develops in >25% of surgical patients who require cardiopulmonary bypass and almost 30% of patients in intensive care units. When ARF is the result of a decrease in blood volume without kidney damage, the condition can often be quickly and completely reversed. When the kidneys have been injured, however, they must heal if the ARF is to resolve . . .
J Pharm Technol 2005;21:188.
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