the journal of Pharmacy Technology the journal of Pharmacy Technology
Abstracts of Back Issues
Home
Home
Back Issues
Author Information
PharmaCE
Acknowledgments
About the journal
Order Form
Customer Service
Advertising Information
Contact Information


EXENATIDE: A NOVEL THERAPEUTIC APPROACH FOR TYPE 2 DIABETES MELLITUS
Amie D McCord

To request full article click here.

OBJECTIVE: To review the pharmacology, pharmacokinetics, clinical efficacy and safety studies, adverse effects, drug interactions, and dosage and administration of exenatide, a novel incretin mimetic agent recently approved for the treatment of type 2 diabetes mellitus.

DATA SOURCES: Information was obtained from MEDLINE searches of the English-language literature (1990-November 2004). Search terms included exenatide, synthetic exendin-4, exendin-4, AC2993, and GLP-1 agonist.

STUDY SELECTION AND DATA EXTRACTION: All available data were reviewed, including animal and human data disseminated as abstracts, clinical trials, review articles, and press releases.

DATA SYNTHESIS: Exenatide is a novel therapeutic agent recently approved for the treatment of type 2 diabetes. The unique pharmacologic profile of exenatide offers a promising adjunctive treatment option for this patient population.

CONCLUSIONS: While the long-term safety and efficacy of this agent are not well documented, the available data indicate the efficacy and safety of exenatide in combination with various oral antidiabetic agents in reducing postprandial glucose concentrations, glycosylated hemoglobin values, and potentially body weight without increasing the risk of hypoglycemia.

J Pharm Technol 2005;21:191-6.

To request full article click here.


Harvey Whitney Books


Harvey Whitney Books

 
 

the journal of Pharmacy Technology
is published by HARVEY WHITNEY BOOKS COMPANY
8044 Montgomery Road, Suite 415, Cincinnati, OH 45236-2919
P.O. Box 42696, Cincinnati, OH 45242-0696 USA
Tel. 513/793-3555, FAX 513/793-3600
Office Hours: 9-5 E.S.T.
Contact Information
All Rights Reserved. Copyright © 1998-