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MEDICAL PROBLEMS: BRIEF
REVIEWSPolycystic Ovary Syndrome Michael J
Katz
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Five to ten percent of women have polycystic
ovary syndrome (PCOS). In PCOS, reproductive hormones do not cycle. Instead,
estrogens and luteinizing hormone (LH) remain at high levels. Women with PCOS
ovulate rarely or not at all, and they do not have regular menstrual periods.
They tend to be overweight and to have excess body hair. Untreated, they will
remain infertile and will be more likely than normal to develop diabetes,
artery disease, and endometrial cancer. Giving a woman with PCOS periodic
progestin supplements can reestablish menstrual cycling and reduce her risk for
serious medical problems. Metformin can reduce her risk for cardiovascular
disease. In addition, drugs that temporarily increase her follicle-stimulating
hormone (FSH) levels can induce ovulation and lead to a normal pregnancy . . .
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